Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208993 | 0.84 | TSHR (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6838116 | 0.79 | SELL (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28199964 | 0.75 | HPGD (0.40) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1760433 | 0.74 | TYR (0.44) | CA1CA2LMNATSHRGAA | |
| SCHEMBL30360391 | 0.74 | TYR (0.44) | CA1CA2LMNATSHRGAA | |
| SCHEMBL157593 | 0.74 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29006247 | 0.74 | CA1 (0.59) | CA1CA2CA9CA12CA7 | |
| SCHEMBL30280931 | 0.74 | CA12 (0.39) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4458299 | 0.74 | KDM4E (0.45) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2242047 | 0.74 | CA12 (0.46) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044314-A1 | N-ACYL SULFAMIC ACID ESTERS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-11-27 | — | — | WO | disclosed |