Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310431 | 1.00 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10080349 | 0.92 | TSHR (0.67) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL29090870 | 0.92 | TSHR (0.67) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9159442 | 0.89 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL17187306 | 0.89 | HCAR2 (0.68) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9159451 | 0.89 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL956149 | 0.89 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Dimethyl Maleate SCHEMBL28099231 | 0.88 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12607041 | 0.83 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12607042 | 0.83 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922739-A | Copolymers comprising polysiloxane macromonomer units, process for their preparation and their use in coating compositions and polymeric moulding compounds | 毕克化学有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107849358-A | Copolymers containing polyether-polysiloxane macromonomer units, process for their preparation and their use in coating compositions and polymer moulding compounds | 毕克化学有限公司 | 2018-03-27 | — | — | CN | disclosed |
| US-5700455-A | MODIFIED HYDROCOLLOIDS | PERMETHYL SPECIALTIES, L.L.C. (US) | 1997-12-23 | — | — | US | disclosed |
| WO-1996017582-A1 | WATER SOLUBLE, BIODEGRADABLE POLYMERIC MATERIALS FOR SKIN CARE, HAIR CARE AND COSMETIC APPLICATIONS | PERMETHYL SPECIALTIES L.L.C. (US) | 1996-06-13 | — | — | WO | disclosed |