Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | CALCR | P30988 | 4/20 | 0.48 |
| ▸ | TFPI | P10646 | 1/20 | 0.48 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893062 | 0.89 | IL23R (0.57) | GLP1RIL23RKISS1RTFPI | |
| SCHEMBL29635074 | 0.89 | F2 (0.59) | GLP1RCRHR1CRHR2CALCRTFPI | |
| SCHEMBL9437223 | 0.88 | GLP1R (0.50) | GLP1RKISS1RCRHR1CRHR2CALCR | |
| SCHEMBL8894013 | 0.86 | TFPI (0.58) | GLP1RIL23RTFPINPY1RNPY2R | |
| SCHEMBL8894949 | 0.85 | BACE1 (0.61) | IL23RKISS1RTFPI | |
| SCHEMBL31462023 | 0.85 | CALCR (0.54) | GLP1RCRHR1CRHR2CALCRVIPR2 | |
| SCHEMBL8894994 | 0.85 | KISS1R (0.59) | IL23RKISS1RVIPR2 | |
| SCHEMBL29974829 | 0.84 | F2 (0.52) | IL23RKISS1RTFPI | |
| SCHEMBL29973963 | 0.84 | F2 (0.52) | IL23RKISS1RTFPI | |
| SCHEMBL30504388 | 0.84 | VIPR1 (0.56) | GLP1RKISS1RCRHR1CRHR2CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618785-A | ANTIISCHEMIC AGENTS, ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS | CENTOCOR, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| WO-1995014787-A1 | PEPTIDE INHIBITORS OF SELECTING BINDING | CENTOCOR, INC. (US) | 1995-06-01 | — | — | WO | disclosed |