Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426415 | 0.86 | MEN1 (1.00) | MEN1KMT2AKCNH2LMNATSHR | |
| SCHEMBL17444669 | 0.85 | MEN1 (0.75) | MEN1KMT2AKCNH2LMNATSHR | |
| SCHEMBL16233165 | 0.81 | MEN1 (0.70) | MEN1KMT2AKCNH2LMNATSHR | |
| SCHEMBL9513269 | 0.81 | KMT2A (0.71) | MEN1KMT2AKCNH2LMNASMN1; SMN2 | |
| SCHEMBL6488922 | 0.81 | SIGMAR1 (0.55) | MEN1KMT2AKCNH2LMNATSHR | |
| SCHEMBL25238918 | 0.81 | MEN1 (0.89) | MEN1KMT2AKCNH2SIGMAR1KDM4E | |
| SCHEMBL17444586 | 0.81 | KMT2A (0.68) | MEN1KMT2AKCNH2LMNATSHR | |
| SCHEMBL29809468 | 0.81 | HPGD (0.59) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL5727652 | 0.81 | HPGD (0.59) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL5655904 | 0.80 | SMN1; SMN2 (0.57) | MEN1KMT2ALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |