Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364293 | 0.79 | ESRRG (0.43) | EPHX2RXRARXRBNR1H4LMNA | |
| SCHEMBL8894269 | 0.76 | SMN1; SMN2 (0.54) | RXRARXRBKDM4ELMNACYP2C19 | |
| SCHEMBL23402375 | 0.74 | HTR1D (0.44) | EPHX2RXRARXRBNR1H4KDM4E | |
| SCHEMBL2365058 | 0.73 | KDM4E (0.39) | EPHX2RXRARXRBNR1H4KDM4E | |
| SCHEMBL15369564 | 0.72 | KDM4E (0.40) | EPHX2RXRARXRBNR1H4KDM4E | |
| SCHEMBL23400064 | 0.72 | HTR1D (0.42) | EPHX2RXRARXRBNR1H4KDM4E | |
| SCHEMBL15800261 | 0.71 | HTR1D (0.44) | EPHX2RXRARXRBNR1H4KDM4E | |
| SCHEMBL3366761 | 0.69 | SMN1; SMN2 (0.51) | RXRARXRBLMNAKMT2AMEN1 | |
| SCHEMBL26802829 | 0.69 | HTR1D (0.45) | EPHX2RXRARXRBNR1H4KDM4E | |
| SCHEMBL8580573 | 0.68 | RXRA (0.71) | EPHX2RXRARXRBNR1H4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |