SCHEMBL8895161

SCHEMBL8895161

CCCCC1(CC)CSc2ccc(OC)cc2C(c2cccc(C(F)(F)F)c2)C1O

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 18/20 0.51
CYP2C19 P33261 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8566165 0.91 SLC10A2 (0.56) SLC10A2
SCHEMBL8892222 0.89 SLC10A2 (0.52) SLC10A2
SCHEMBL8204364 0.88 SLC10A2 (0.64) SLC10A2
SCHEMBL8891513 0.84 SLC10A2 (0.62) SLC10A2
SCHEMBL8568974 0.84 SLC10A2 (0.67) SLC10A2
SCHEMBL8201532 0.82 SLC10A2 (0.64) SLC10A2
SCHEMBL8892089 0.81 SLC10A2 (0.49) SLC10A2
SCHEMBL6219856 0.81 SLC10A2 (0.79) SLC10A2
SCHEMBL6225745 0.81 SLC10A2 (0.79) SLC10A2
SCHEMBL6219859 0.81 SLC10A2 (0.79) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033882-A1 NOVEL BENZOTHIEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT AND TAUROCHOLATE UPTAKE G.D. SEARLE AND CO. (US) 1997-09-18 WO disclosed