SCHEMBL8895175

SCHEMBL8895175

CC(C)N(C(=O)c1ccc(OCCCOc2c(Cl)cc(O)cc2Cl)cc1)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 3/20 0.47
SRD5A2 P31213 2/20 0.43
LTB4R2 Q9NPC1 1/20 0.42
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
PLA2G4B P0C869 1/20 0.37
RARB P10826 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8896987 0.82 POLB (0.45) HRH3L3MBTL1TP53PLA2G4B
SCHEMBL8405795 0.81 CA12 (0.50) L3MBTL1GAAMAPK1PLA2G4BRARB
SCHEMBL8895868 0.81 TSHR (0.49) HPGDGAATP53PLA2G4B
Hydrochloric Acid SCHEMBL8994932 0.80 LTB4R (0.65) LTB4RLTB4R2HRH3
SCHEMBL8408614 0.80 MAPT (0.60) MEN1KMT2AL3MBTL1GAATP53
SCHEMBL8895035 0.80 POLB (0.45) HRH3L3MBTL1TP53PLA2G4B
SCHEMBL8894156 0.79 MAOB (0.44) MEN1KMT2AHRH3HPGDNPSR1
SCHEMBL8897559 0.79 F2 (0.42) MEN1KMT2AL3MBTL1
SCHEMBL8408530 0.78 PLAU (0.44) KMT2AHPGDL3MBTL1TP53MAPK1
SCHEMBL8895921 0.76 LSS (0.42) MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997027173-A2 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-31 WO disclosed