Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539095 | 0.79 | TSHR (0.52) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL29013244 | 0.78 | TSHR (0.46) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL14865334 | 0.78 | TSHR (0.46) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL3447711 | 0.77 | TSHR (0.44) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL14563343 | 0.77 | TSHR (0.44) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL5505303 | 0.76 | TSHR (0.48) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL24229986 | 0.76 | TSHR (0.48) | TSHREPHX2LMNAKMT2AMEN1 | |
| SCHEMBL14563380 | 0.76 | TSHR (0.43) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| SCHEMBL29087328 | 0.74 | TSHR (0.46) | TSHRHSD17B10EPHX2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL25217893 | 0.74 | LMNA (0.48) | TSHREPHX2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696282-A | CATALYTIC REACTION OF A HYDROGEN SULFIDE OR MERCAPTAN WITH UNSATURATED CARBONYL OR CYANO COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1997-12-09 | — | — | US | claimed |