Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893481 | 1.00 | LMNA (0.62) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8894782 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8895965 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8896504 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8894179 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8893867 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8895240 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8894838 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8896046 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA | |
| SCHEMBL8894538 | 0.98 | LMNA (0.60) | LMNAPOLBALDH1A1GAANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |