Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.68 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882257 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL8896667 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL1889622 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL8896941 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL11249237 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL7828971 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL7841880 | 1.00 | DGKA (0.68) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL616258 | 0.98 | DGKA (0.64) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL7840375 | 0.94 | DGKA (0.71) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL1888899 | 0.94 | DGKA (0.71) | DGKANAAAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |