Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.74 |
| ▸ | PNP | P00491 | 11/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | EDNRA | P25101 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | POLG | P54098 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896272 | 0.99 | HPRT1 (0.72) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8896276 | 0.91 | HPRT1 (0.81) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8898386 | 0.90 | HPRT1 (0.80) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8708928 | 0.89 | HPRT1 (0.66) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL23859843 | 0.85 | HPRT1 (1.00) | HPRT1PNPUSP2TSHREDNRA | |
| Gs-438 SCHEMBL64567 | 0.85 | POLB (0.80) | HPRT1PNPPOLG | |
| SCHEMBL8708946 | 0.85 | HPRT1 (0.69) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8709216 | 0.84 | HPRT1 (0.67) | HPRT1PNPUSP2TSHREDNRA | |
| Acyclovir SCHEMBL145606 | 0.84 | PNP (0.91) | HPRT1PNPUSP2TSHREDNRA | |
| Acyclovir SCHEMBL543440 | 0.84 | PNP (0.91) | HPRT1PNPUSP2TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | claimed |