Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.80 |
| ▸ | PNP | P00491 | 10/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | EDNRA | P25101 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | HBB | P68871 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | POLG | P54098 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | POLA1 | P09884 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896276 | 0.99 | HPRT1 (0.81) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8895437 | 0.90 | HPRT1 (0.74) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL11313321 | 0.89 | PNP (0.86) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8896272 | 0.89 | HPRT1 (0.72) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL23859843 | 0.89 | HPRT1 (1.00) | HPRT1PNPUSP2TSHREDNRA | |
| Gs-438 SCHEMBL64567 | 0.89 | POLB (0.80) | HPRT1PNPPOLGPOLBPOLA1 | |
| SCHEMBL29370760 | 0.88 | PNP (0.87) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8905172 | 0.88 | HPRT1 (0.71) | HPRT1PNPPOLGPOLBPOLA1 | |
| SCHEMBL11308931 | 0.88 | PNP (0.88) | HPRT1PNPUSP2TSHREDNRA | |
| Acyclovir SCHEMBL145614 | 0.87 | PNP (0.91) | HPRT1PNPUSP2TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | claimed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | claimed |