Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012037 | 0.84 | CYP2D6 (0.59) | CYP2D6SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL4681142 | 0.84 | CYP2D6 (0.59) | CYP2D6SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL8380944 | 0.82 | EPHX1 (0.37) | CYP2D6ALDH1A1POLBHTTKMT2A | |
| SCHEMBL19795862 | 0.73 | CYP2D6 (0.47) | CYP2D6SMN1; SMN2ALDH1A1KMT2ATDP1 | |
| SCHEMBL18011995 | 0.72 | BACE1 (0.46) | CYP2D6SMN1; SMN2ALDH1A1POLBHTT | |
| SCHEMBL6736590 | 0.70 | SMN1; SMN2 (0.51) | CYP2D6SMN1; SMN2ALDH1A1POLBTDP1 | |
| SCHEMBL6739703 | 0.70 | SMN1; SMN2 (0.51) | CYP2D6SMN1; SMN2ALDH1A1POLBTDP1 | |
| SCHEMBL20901348 | 0.70 | CYP2D6 (0.47) | CYP2D6SMN1; SMN2ALDH1A1POLBTSHR | |
| SCHEMBL8977701 | 0.70 | SLC6A2 (0.46) | CYP2D6ALDH1A1HTTKMT2ATDP1 | |
| SCHEMBL10001744 | 0.68 | TSHR (0.67) | CYP2D6SMN1; SMN2ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |