Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739705 | 0.67 | ATM (0.42) | POLBALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL6736592 | 0.67 | ATM (0.42) | POLBALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL6778355 | 0.63 | HSD17B2 (0.56) | — | |
| SCHEMBL6778353 | 0.63 | HSD17B2 (0.56) | — | |
| SCHEMBL8380944 | 0.62 | EPHX1 (0.37) | POLBEPHX1KDM4EALDH1A1ALOX12 | |
| SCHEMBL3649071 | 0.61 | SLC6A2 (0.49) | POLBSMN1; SMN2HTTRIPK1 | |
| SCHEMBL9016269 | 0.61 | TSHR (0.44) | HTR1ATSHRKMT2AMEN1 | |
| SCHEMBL5298515 | 0.61 | TSHR (0.44) | HTR1ATSHRKMT2AMEN1 | |
| SCHEMBL13184074 | 0.61 | TSHR (0.44) | HTR1ATSHRKMT2AMEN1 | |
| SCHEMBL1743559 | 0.61 | TSHR (0.44) | HTR1ATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |