Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | GRN | P28799 | 2/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313039 | 0.98 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4313036 | 0.98 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4134832 | 0.86 | CNR2 (0.43) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8895540 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4145751 | 0.84 | PSEN1 (0.44) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4313026 | 0.83 | BCHE (0.49) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4313021 | 0.83 | BCHE (0.49) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4317981 | 0.81 | BCHE (0.50) | ALDH1A1KMT2AMEN1LMNAFOLH1 | |
| SCHEMBL4317976 | 0.81 | BCHE (0.50) | ALDH1A1KMT2AMEN1LMNAFOLH1 | |
| SCHEMBL4058648 | 0.81 | SMN1; SMN2 (0.42) | KMT2ALMNAGRNSORT1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791264-B2 | Benzenesulfonamide compounds and their use as blockers of calcium channels | PURDUE PHARMA L.P. (US) | 2014-07-29 | — | — | US | disclosed |
| EP-0584374-B1 | PEPTIDE WHICH INHIBITS PHOSPHOLIPASE C | KYOWA HAKKO KOGYO KK (JP) | 1997-09-24 | — | — | EP | disclosed |