Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894539 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL7684369 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL8893338 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL1915457 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL12248758 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL7228762 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL27566802 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL8896650 | 0.73 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL5327111 | 0.73 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL1821573 | 0.73 | CYP1A1 (0.75) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611766-A1 | Polysubstituted 2-amido thiazoles derivatives, process for their preparation, pharmaceutical compositions and utilization for the preparation of a medicament | SANOFI (FR) | 1994-08-24 | — | — | EP | claimed |
| US-5656648-A | TREATMENT OF PATHOLOGIES NECESSITATING STIMULATION OF CHOLECYSTOKININ-A RECEPTORS BY TOTAL OR PARTIAL AGONIST EFFECT | SANOFI (FR) | 1997-08-12 | — | — | US | disclosed |
| EP-0611766-A1 | Polysubstituted 2-amido thiazoles derivatives, process for their preparation, pharmaceutical compositions and utilization for the preparation of a medicament | SANOFI (FR) | 1994-08-24 | — | — | EP | disclosed |