Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898393 | 0.75 | ATR (0.44) | CTSSCTSKIKBKBXDHALDH1A1 | |
| SCHEMBL11370778 | 0.74 | CHEK1 (0.53) | USP8ADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL11368597 | 0.72 | ERBB2 (0.47) | IKBKBUSP8ADORA2AALDH1A1MEN1 | |
| SCHEMBL8896372 | 0.72 | CTSS (0.46) | CTSSCTSKIKBKBXDHADORA2A | |
| SCHEMBL8898622 | 0.70 | PIK3CG (0.43) | IKBKBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28823040 | 0.69 | DPP4 (0.51) | USP8ADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL10087551 | 0.68 | HSD17B10 (0.38) | USP8ADORA2AALDH1A1 | |
| SCHEMBL11809427 | 0.68 | CHEK1 (0.53) | USP8ADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL21722354 | 0.65 | ADORA2A (0.58) | ADORA2AALDH1A1MEN1KMT2AADORA1 | |
| SCHEMBL8649829 | 0.65 | IKBKB (0.40) | CTSSCTSKIKBKBXDHADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |