Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8895987

NC1c2ccccc2-c2ccccc21.O=C(O)C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.46
HTR2B P41595 2/20 0.46
CES1 P23141 2/20 0.45
DPP8 Q6V1X1 2/20 0.40
DPP7 Q9UHL4 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
POLB P06746 1/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
EDNRA P25101 2/20 0.38
EDNRB P24530 1/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27796355 0.82 POLB (0.52) HTR7HTR2BHDAC3HDAC4HDAC7
Trifluoroacetic Acid SCHEMBL8895982 0.81 ATM (0.49) HTR7HTR2BCES1DPP8DPP7
Trifluoroacetic Acid SCHEMBL6621775 0.80 EDNRB (0.36) HTR7HTR2BCES1DPP8DPP7
SCHEMBL353865 0.78 HTR2A (0.52) HTR7HTR2BHDAC3HDAC4HDAC7
SCHEMBL29444048 0.78 HTR2A (0.52) HTR7HTR2BHDAC3HDAC4HDAC7
SCHEMBL30410319 0.78 HTR2A (0.52) HTR7HTR2BHDAC3HDAC4HDAC7
Trifluoroacetic Acid SCHEMBL29065252 0.78 HTR2A (0.42) CES1DPP8DPP7HDAC3HDAC4
SCHEMBL22270015 0.76 HTR2A (0.50) HTR7HTR2BCES1HDAC3HDAC4
Water SCHEMBL28455469 0.76 HTR2A (0.50) HTR7HTR2BHDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL355946 0.76 HTR2A (0.50) HTR7HTR2BHDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686421-A INHIBITING PLATELET AGGREGATION HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-11 US disclosed