Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143561 | 0.87 | ATM (0.61) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL30250175 | 0.87 | ATM (0.61) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| Trifluoroacetic Acid SCHEMBL8895987 | 0.81 | HTR7 (0.46) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL18748394 | 0.77 | HDAC3 (0.52) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL30249875 | 0.76 | HDAC3 (0.52) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL18952633 | 0.76 | HDAC3 (0.52) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL7539130 | 0.76 | ATM (0.40) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| Trifluoroacetic Acid SCHEMBL29065252 | 0.75 | HTR2A (0.42) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL7539128 | 0.75 | ATM (0.39) | ATMHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL2763555 | 0.72 | ATM (0.46) | ATMHDAC3HDAC4HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686421-A | INHIBITING PLATELET AGGREGATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | disclosed |