Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515138 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL9207348 | 0.78 | TSHR (0.50) | ALDH1A1KDM4ETSHRCYP1A2CYP2C19 | |
| SCHEMBL3080086 | 0.77 | TSHR (0.49) | ALDH1A1TSHRCYP1A2CYP2C19THRB | |
| SCHEMBL6667989 | 0.77 | TSHR (0.49) | ALDH1A1TSHRCYP1A2CYP2C19PTPRF | |
| SCHEMBL678471 | 0.74 | TSHR (0.52) | ALDH1A1TSHRCYP1A2CYP2C19LOXL2 | |
| SCHEMBL11327905 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL1627332 | 0.72 | TSHR (0.53) | ALDH1A1KDM4ETSHRCYP2C19LOXL2 | |
| SCHEMBL4171756 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL20347417 | 0.71 | PPARG (0.43) | ALDH1A1KDM4ETSHRCYP1A2CYP2C19 | |
| SCHEMBL1717816 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631281-A | COMPOUNDS FOR TREATMENT OF ANXIETY WITH INDOLE AMIDES | WARNER-LAMBERT COMPANY (US) | 1997-05-20 | — | — | US | disclosed |