Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540359 | 1.00 | ALDH1A1 (0.42) | ALDH1A1THRBATML3MBTL1HCAR2 | |
| SCHEMBL8761172 | 0.98 | HCAR2 (0.42) | ALDH1A1THRBATML3MBTL1HCAR2 | |
| SCHEMBL3974696 | 0.90 | — | — | |
| SCHEMBL9744705 | 0.81 | HCAR2 (0.47) | ALDH1A1THRBATML3MBTL1HCAR2 | |
| SCHEMBL1581948 | 0.81 | HCAR2 (0.47) | ALDH1A1THRBATML3MBTL1HCAR2 | |
| SCHEMBL1581950 | 0.81 | HCAR2 (0.47) | ALDH1A1THRBATML3MBTL1HCAR2 | |
| SCHEMBL2075804 | 0.81 | TSHR (0.42) | ALDH1A1L3MBTL1HCAR2NPSR1KMT2A | |
| SCHEMBL14363086 | 0.81 | HCAR2 (0.47) | ALDH1A1THRBATML3MBTL1HCAR2 | |
| SCHEMBL5198674 | 0.81 | HCAR2 (0.38) | ALDH1A1HCAR2NPSR1TSHR | |
| SCHEMBL9744701 | 0.81 | HCAR2 (0.47) | ALDH1A1THRBATML3MBTL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |