Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8897736 | 0.84 | KHK (0.37) | HRH3EPHX2S1PR1F10HPN | |
| SCHEMBL8985758 | 0.81 | HRH3 (0.39) | HRH3EPHX2ALDH1A1CYP3A4 | |
| SCHEMBL8895805 | 0.81 | HRH3 (0.39) | HRH3EPHX2ALDH1A1CYP3A4 | |
| SCHEMBL7282065 | 0.81 | HRH3 (0.41) | HRH3EPHX2S1PR1F10HPN | |
| SCHEMBL7273643 | 0.80 | HRH3 (0.43) | HRH3EPHX2S1PR1F10HPN | |
| Hydrochloric Acid SCHEMBL7394184 | 0.80 | HRH3 (0.41) | HRH3EPHX2S1PR1F10HPN | |
| SCHEMBL7280320 | 0.78 | KHK (0.48) | HRH3EPHX2S1PR1F10ALDH1A1 | |
| SCHEMBL7272988 | 0.77 | F10 (0.54) | F10HPNPRSS1PRSS2PRSS3 | |
| SCHEMBL7282879 | 0.77 | F10 (0.46) | HRH3S1PR1F10HPNPRSS1 | |
| SCHEMBL8575577 | 0.75 | HRH3 (0.42) | HRH3EPHX2S1PR1F10HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |