SCHEMBL8896411

SCHEMBL8896411

CC(NC=O)C(Cc1ccc(Cl)c(Cl)c1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 7/20 0.60
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SIGMAR1 Q99720 1/20 0.44
PNMT P11086 1/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
PLA2G1B P04054 1/20 0.38
POLB P06746 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
CCR2 P41597 2/20 0.38
MME P08473 1/20 0.38
PTPN5 P54829 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626206 0.86 FDFT1 (0.63) FDFT1MEN1KMT2ACYP1A2CYP2C9
Hydrochloric Acid SCHEMBL8623992 0.85 FDFT1 (0.62) FDFT1MEN1KMT2ACYP1A2CYP2C9
Hydrochloric Acid SCHEMBL8623990 0.85 FDFT1 (0.62) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8619616 0.82 FDFT1 (0.59) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8621271 0.80 FDFT1 (0.55) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8621281 0.80 FDFT1 (0.55) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8620980 0.77 FDFT1 (0.82) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8625596 0.77 FDFT1 (0.82) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8623136 0.77 FDFT1 (0.72) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8624778 0.77 FDFT1 (0.72) FDFT1MEN1KMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5606101-A INTERMEDIATES FOR SQUALENE SYNTHASE INHIBITORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-02-25 US disclosed