Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 7/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626206 | 0.87 | FDFT1 (0.63) | FDFT1SIGMAR1CYP1A2CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL8623990 | 0.86 | FDFT1 (0.62) | FDFT1SIGMAR1LMNAALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL8623992 | 0.86 | FDFT1 (0.62) | FDFT1SIGMAR1LMNAALDH1A1MAPK1 | |
| SCHEMBL8625050 | 0.83 | FDFT1 (0.47) | FDFT1SIGMAR1LMNAALDH1A1MAPK1 | |
| SCHEMBL8896411 | 0.82 | FDFT1 (0.60) | FDFT1SIGMAR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8621281 | 0.81 | FDFT1 (0.55) | FDFT1SIGMAR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8621271 | 0.81 | FDFT1 (0.55) | FDFT1SIGMAR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8624863 | 0.78 | FDFT1 (0.51) | FDFT1SIGMAR1LMNAALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL8623994 | 0.78 | FDFT1 (0.53) | FDFT1SIGMAR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8623156 | 0.78 | SIGMAR1 (0.44) | FDFT1SIGMAR1CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |