Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792839 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL9757960 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1796035 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL2925438 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1795316 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1792845 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1795318 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1796039 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL4097875 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL11327565 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730405-A4 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORP (US) | 1997-02-19 | — | — | EP | disclosed |
| EP-0730405-A1 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORPORATION (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014381-A1 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORPORATION (US) | 1995-06-01 | — | — | WO | disclosed |