Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792839 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL9757960 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1796035 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL2925438 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1795316 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1792845 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1795318 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL1796039 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL8896468 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 | |
| SCHEMBL11327565 | 1.00 | CA12 (0.50) | CA12CA1CA9SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487826-A | EXCELLENT SHELF LIFE AND HEAT SENSITIVITY | TOPPAN PRINTING CO., LTD. (JP) | 1984-12-11 | — | — | US | claimed |
| JP-62035876-A | — | — | None | — | — | JP | disclosed |
| CN-102791798-B | Heat-resistant aging polymeric amide | BASF SE (DE) | 2015-09-09 | — | — | CN | disclosed |
| CN-102666667-B | Functionalized highly branched melamine-polyamine polymers | BASF SE | 2015-03-04 | — | — | CN | disclosed |
| CN-102066451-B | Hyperbranched polymers and oligomers containing terminal amino groups as curing agents for epoxy resins | BASF SE | 2014-08-06 | — | — | CN | disclosed |
| CN-102791798-A | Polyamides resistant to hot ageing | BASF SE | 2012-11-21 | — | — | CN | disclosed |
| CN-102666667-A | Functionalized highly branched melamine-polyamine polymers | BASF SE | 2012-09-12 | — | — | CN | disclosed |
| CN-102066451-A | Hyperbranched polymers and oligomers containing terminal amino groups as curing agents for epoxy resins | BASF SE | 2011-05-18 | — | — | CN | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| JP-S6235876-A | PHOTO-FIXABLE TYPE THERMAL RECORDING MEDIUM | TOMOEGAWA PAPER CO LTD | 1987-02-16 | — | — | JP | disclosed |
| EP-0084890-B1 | DIAZOTYPE HEAT DEVELOPMENT RECORDING MEDIUM | Toppan Printing Co., Ltd. (JP) | 1986-05-21 | — | — | EP | disclosed |
| US-4487826-A | EXCELLENT SHELF LIFE AND HEAT SENSITIVITY | TOPPAN PRINTING CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| EP-0084890-A1 | Diazotype heat development recording medium | Toppan Printing Co., Ltd. (JP) | 1983-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | CA12 2835/4885CA1 3081/4885CA9 1622/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | CA12 3511/4885CA1 3572/4885CA9 1516/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | CA12 3323/4885CA1 3665/4885CA9 2125/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | CA12 2752/4885CA1 2285/4885CA9 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.