Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896103 | 1.00 | TBXAS1 (0.53) | TBXAS1TBXA2RALDH1A1TP53GAA | |
| SCHEMBL8897096 | 0.99 | TBXAS1 (0.52) | TBXAS1TBXA2RALDH1A1TP53GAA | |
| SCHEMBL8895178 | 0.96 | TBXAS1 (0.52) | TBXAS1TBXA2RALDH1A1TP53GAA | |
| SCHEMBL8895739 | 0.94 | TBXAS1 (0.52) | TBXAS1TBXA2RALDH1A1TP53GAA | |
| SCHEMBL8419579 | 0.91 | TBXAS1 (0.50) | TBXAS1TBXA2R | |
| SCHEMBL8894922 | 0.91 | TBXAS1 (0.50) | TBXAS1TBXA2RALDH1A1ATML3MBTL1 | |
| SCHEMBL8895059 | 0.91 | TBXAS1 (0.50) | TBXAS1TBXA2RALDH1A1ATML3MBTL1 | |
| SCHEMBL8894873 | 0.91 | TBXAS1 (0.50) | TBXAS1TBXA2RALDH1A1ATML3MBTL1 | |
| SCHEMBL8895793 | 0.91 | TBXAS1 (0.50) | TBXAS1TBXA2RALDH1A1ATML3MBTL1 | |
| SCHEMBL8896251 | 0.90 | TBXAS1 (0.52) | TBXAS1TBXA2RALDH1A1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |