Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428122 | 0.85 | MEN1 (0.54) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2999740 | 0.83 | MAPT (0.57) | MAPTGAAHTTJMJD7CA1 | |
| SCHEMBL3024109 | 0.82 | ALDH1A1 (0.69) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL28546053 | 0.81 | MAPT (0.47) | MAPTGAAKCNH2HTTJMJD7 | |
| SCHEMBL26640734 | 0.80 | HTT (0.48) | MAPTGAAKCNH2ALDH1A1HTT | |
| SCHEMBL10494766 | 0.80 | MAPT (0.53) | MAPTGAAHTTJMJD7CA1 | |
| SCHEMBL8890664 | 0.78 | ALDH1A1 (0.46) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL17230502 | 0.78 | CA12 (0.51) | MAPTRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25418076 | 0.78 | CA1 (0.50) | MAPTGAAKCNH2RAB9AALDH1A1 | |
| SCHEMBL3001018 | 0.78 | CA1 (0.58) | MAPTGAAALDH1A1HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |