Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894350 | 0.98 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8897155 | 0.98 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8895385 | 0.98 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8894732 | 0.80 | LMNA (0.44) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL268391 | 0.79 | LMNA (0.47) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8896073 | 0.79 | LMNA (0.47) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8893692 | 0.79 | LMNA (0.47) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8408217 | 0.78 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL6066259 | 0.78 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL465490 | 0.78 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |