Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8896489 | 0.98 | MEN1 (0.45) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8895096 | 0.87 | MEN1 (0.59) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8897948 | 0.85 | MEN1 (0.57) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14868710 | 0.84 | TSHR (0.47) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8897145 | 0.78 | MEN1 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1040794 | 0.77 | CYP2C9 (0.58) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8898569 | 0.76 | MEN1 (0.50) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14868712 | 0.76 | MEN1 (0.47) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9666366 | 0.76 | CYP2C9 (0.56) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8895813 | 0.75 | SMN1; SMN2 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | claimed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |