Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8897948 | 0.98 | MEN1 (0.57) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL8897145 | 0.89 | MEN1 (0.51) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL1040794 | 0.89 | CYP2C9 (0.58) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| Hydrochloric Acid SCHEMBL8898569 | 0.88 | MEN1 (0.50) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| Hydrochloric Acid SCHEMBL9666366 | 0.87 | CYP2C9 (0.56) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL8896844 | 0.87 | MEN1 (0.46) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL14868710 | 0.87 | TSHR (0.47) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL564192 | 0.86 | MEN1 (0.57) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL29373341 | 0.85 | LMNA (0.50) | MEN1KMT2ACYP2C9CYP2C19HPGD | |
| SCHEMBL454852 | 0.85 | LMNA (0.50) | MEN1KMT2ACYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | claimed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |