Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 3/20 | 0.55 |
| ▸ | FCER2 | P06734 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30164250 | 1.00 | LTA4H (0.56) | LTA4HRENFCER2MMP1MME | |
| Trifluoroacetic Acid SCHEMBL29531895 | 1.00 | LTA4H (0.56) | LTA4HRENFCER2MMP1MME | |
| SCHEMBL12057953 | 0.94 | LTA4H (0.62) | LTA4HFCER2MMP1MMEMMP2 | |
| SCHEMBL30626017 | 0.94 | LTA4H (0.62) | LTA4HFCER2MMP1MMEMMP2 | |
| SCHEMBL2487473 | 0.94 | LTA4H (0.62) | LTA4HFCER2MMP1MMEMMP2 | |
| SCHEMBL12038997 | 0.94 | LTA4H (0.62) | LTA4HFCER2MMP1MMEMMP2 | |
| SCHEMBL31185441 | 0.94 | LTA4H (0.62) | LTA4HFCER2MMP1MMEMMP2 | |
| Hydrochloric Acid SCHEMBL31115145 | 0.92 | LTA4H (0.61) | LTA4HFCER2MMP1MMEERAP2 | |
| Acetic Acid SCHEMBL31115136 | 0.92 | LTA4H (0.61) | LTA4HFCER2MMP1MMEERAP2 | |
| Acetic Acid SCHEMBL31115148 | 0.92 | LTA4H (0.61) | LTA4HFCER2MMP1MMEERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686422-A | Synthetic inhibitors of mammalian collagenase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0358660-B1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RES CORP TECHNOLOGIES INC (US) | 1994-05-25 | — | — | EP | disclosed |
| EP-0358660-A4 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | — | 1991-01-09 | — | — | EP | disclosed |
| EP-0358660-A1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE. | RES CORP TECHNOLOGIES INC (US) | 1990-03-21 | — | — | EP | disclosed |
| WO-1988006890-A1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-09-22 | — | — | WO | disclosed |