SCHEMBL8897053

SCHEMBL8897053

O=CNC[C@H](O)C(=O)OC=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3665923 0.81 ADH1B (0.44) ADH1BADH1CADH1A
SCHEMBL3667042 0.78 ADH1B (0.41) ADH1BADH1CADH1A
SCHEMBL3670262 0.75 ADH1B (0.39) ADH1BADH1CADH1A
SCHEMBL8897050 0.73
SCHEMBL3669070 0.73
SCHEMBL1002608 0.73
SCHEMBL557704 0.70
SCHEMBL3667152 0.69 SLC6A2 (0.49) ADH1BADH1CADH1A
SCHEMBL23294041 0.67 TET2 (0.32)
SCHEMBL14121139 0.67 ADH1B (0.43) ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547031-B1 N-protected-(S)-isoserine compounds SCHERING CORP (US) 1997-04-23 EP claimed
EP-0547031-A1 N-protected-(S)-isoserine compounds SCHERING CORPORATION (US) 1993-06-16 EP claimed
EP-0405820-A2 Improved process for preparing isepamicin SCHERING CORPORATION (US) 1991-01-02 EP claimed
EP-0547031-B1 N-protected-(S)-isoserine compounds SCHERING CORP (US) 1997-04-23 EP disclosed
US-5539121-A 2-formylmercaptobenzothiazole SCHERING CORPORATION (US) 1996-07-23 US disclosed
US-5442047-A Process for preparing isepamicin SCHERING CORPORATION (US) 1995-08-15 US disclosed
EP-0405820-B1 Improved process for preparing isepamicin SCHERING CORP (US) 1994-04-13 EP disclosed
EP-0547031-A1 N-protected-(S)-isoserine compounds SCHERING CORPORATION (US) 1993-06-16 EP disclosed
EP-0405820-A2 Improved process for preparing isepamicin SCHERING CORPORATION (US) 1991-01-02 EP disclosed