Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.53 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264079 | 0.87 | ACE (0.65) | ACESLC1A3SLC1A2SLC1A1ANPEP | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL4755513 | 0.86 | SLC1A3 (0.73) | ACESLC1A3SLC1A2SLC1A1NPC1 | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL305323 | 0.86 | SLC1A3 (0.73) | ACESLC1A3SLC1A2SLC1A1NPC1 | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL2919214 | 0.86 | SLC1A3 (0.73) | ACESLC1A3SLC1A2SLC1A1NPC1 | |
| (2R,3R)-2,3-Dibenzylsuccinic Acid SCHEMBL7289849 | 0.86 | SLC1A3 (0.73) | ACESLC1A3SLC1A2SLC1A1NPC1 | |
| SCHEMBL27471453 | 0.83 | ACE (0.47) | ACESLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL6940090 | 0.83 | ACE (0.47) | ACESLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL5511480 | 0.82 | SLC1A3 (0.63) | ACESLC1A3SLC1A2SLC1A1NPC1 | |
| SCHEMBL883357 | 0.82 | SLC1A3 (0.63) | ACESLC1A3SLC1A2SLC1A1NPC1 | |
| SCHEMBL24252143 | 0.81 | SLC1A3 (0.61) | ACESLC1A3SLC1A2SLC1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |