Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.51 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897119 | 0.87 | ACE (0.58) | ACESLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL21264080 | 0.86 | ACE (0.50) | ACETRPA1ANPEPRNPEPDNPEP | |
| SCHEMBL21598301 | 0.84 | ACE (0.62) | ACETRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21264005 | 0.82 | MMP8 (0.51) | ACETRPA1 | |
| SCHEMBL4986173 | 0.82 | SLC1A3 (0.56) | ACETRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13880222 | 0.81 | ACE (0.55) | ACETRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3928753 | 0.78 | CYP1A2 (0.70) | SLC1A3SLC1A2SLC1A1ANPEPRNPEP | |
| SCHEMBL5511480 | 0.77 | SLC1A3 (0.63) | ACETRPA1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL473506 | 0.77 | TRPA1 (0.59) | ACETRPA1CYP1A2CYP2D6 | |
| SCHEMBL883357 | 0.77 | SLC1A3 (0.63) | ACETRPA1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154663-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2019-08-15 | — | — | WO | disclosed |