SCHEMBL8897310

SCHEMBL8897310

COc1cc(OC)nc(Oc2cccc(-c3cccc(C)n3)c2C(=O)O)n1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
GAA P10253 1/20 0.48
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7850805 0.91 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL8912673 0.84 CYP1A2 (0.43) CYP1A2CYP3A4CYP2C9CYP2C19GAA
Bispyribac SCHEMBL65725 0.84 CA12 (0.56) CYP1A2CYP3A4CYP2C9CYP2C19GAA
Bispyribac SCHEMBL4895772 0.84 CA12 (0.56) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9215334 0.83 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL13197224 0.83 CYP1A2 (0.51) CYP1A2CYP3A4CYP2C9CYP2C19GAA
Bispyribac SCHEMBL2114791 0.82 CA12 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19GAA
Bispyribac SCHEMBL238471 0.82 CA12 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19GAA
Bispyribac SCHEMBL9195440 0.82 CA12 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9754398 0.81 CYP1A2 (0.51) CYP1A2CYP3A4CYP2C9CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627136-A HERBICIDES, ANTIGROWTH REGULATORS AND PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1997-05-06 US disclosed
EP-0656357-A1 Substituted pyridyl-n-oxide salicylic aldehyde and salicylic acid derivatives, methods for preparing them and their use as herbicides BASF Aktiengesellschaft (DE) 1995-06-07 EP disclosed