Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895934 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDCHRM2MEN1 | |
| SCHEMBL8895813 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDCHRM2MEN1 | |
| Hydrochloric Acid SCHEMBL8899651 | 0.99 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDCHRM2MEN1 | |
| Hydrochloric Acid SCHEMBL8894995 | 0.99 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDCHRM2MEN1 | |
| Hydrochloric Acid SCHEMBL8895770 | 0.99 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDCHRM2MEN1 | |
| SCHEMBL457779 | 0.90 | KDM4E (0.48) | SMN1; SMN2ALDH1A1HPGDCHRM2MEN1 | |
| Hydrochloric Acid SCHEMBL4460799 | 0.86 | L3MBTL1 (0.49) | ALDH1A1HPGDCHRM2LMNAHDAC3 | |
| Hydrochloric Acid SCHEMBL4476184 | 0.86 | L3MBTL1 (0.49) | ALDH1A1HPGDCHRM2LMNAHDAC3 | |
| Hydrochloric Acid SCHEMBL4471650 | 0.86 | ESR1 (0.46) | ALDH1A1CHRM2LMNAHDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL4484092 | 0.86 | ESR1 (0.46) | ALDH1A1CHRM2LMNAHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0507317-A2 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | claimed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | disclosed |