Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP5 | P51878 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678316 | 0.97 | LMNA (0.67) | LMNAHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7592944 | 0.87 | HSP90AB1 (0.66) | LMNAHTTALDH1A1HSP90AB1MAPT | |
| Oxalic Acid SCHEMBL6232933 | 0.83 | HSP90AB1 (0.59) | LMNAHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9685255 | 0.83 | HTT (1.00) | LMNAHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4978720 | 0.82 | LMNA (0.53) | LMNAHTTHSP90AB1MAPTTP53 | |
| SCHEMBL8177832 | 0.81 | DRD4 (0.65) | LMNAHTTALDH1A1L3MBTL1HSP90AB1 | |
| SCHEMBL9686179 | 0.80 | HTT (0.71) | LMNAHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28522410 | 0.80 | LMNA (0.56) | LMNAHTTHSP90AB1MAPTTP53 | |
| SCHEMBL9686181 | 0.80 | HTT (0.71) | LMNAHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9684395 | 0.80 | HTT (0.68) | LMNAHTTALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799617-A2 | Therapeutic agent for neurological diseases | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-4959368-A | PYRIMIDINE DERIVATIVES | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1990-09-25 | — | — | US | disclosed |
| EP-0257102-A1 | AGENTS FOR TREATING NEUROPHATHY | Mitsui Chemicals, Inc. (JP) | 1988-03-02 | — | — | EP | disclosed |