Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900827 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL8898861 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL8899759 | 0.90 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL8899765 | 0.87 | MAPK1 (0.46) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL8900168 | 0.85 | NPC1 (0.42) | SMN1; SMN2ALDH1A1MAPK1TSHRRAB9A | |
| SCHEMBL3426330 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL8900852 | 0.85 | GSK3B (0.45) | SMN1; SMN2ALDH1A1MAPK1TSHRRAB9A | |
| SCHEMBL8897848 | 0.84 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL4418400 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1MAPK1TSHRFKBP1A | |
| SCHEMBL4424512 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1MAPK1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629356-A | PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE | CIBA GEIGY CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| US-5554663-A | α-aminoacetophenones as photoinitiators | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0284561-B1 | ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5077402-A | For photocuring pigmented systems; printing inks, lacquers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0284561-A2 | Alpha-aminoacetophenones as photo initiators | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |