Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897683 | 1.00 | EPHX2 (0.57) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL3921783 | 0.86 | EPHX2 (0.56) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL3928604 | 0.86 | EPHX2 (0.56) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL9860844 | 0.85 | LPAR1 (0.67) | EPHX2ALDH1A1MAPTCNR1MEN1 | |
| SCHEMBL9860855 | 0.85 | LPAR1 (0.67) | EPHX2ALDH1A1MAPTCNR1MEN1 | |
| SCHEMBL3363761 | 0.85 | EPHX2 (0.55) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL3362347 | 0.85 | EPHX2 (0.55) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL3363709 | 0.85 | EPHX2 (0.55) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL12179613 | 0.83 | EPHX2 (0.61) | EPHX2ALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL14760438 | 0.83 | EPHX2 (0.61) | EPHX2ALDH1A1MAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730405-A4 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORP (US) | 1997-02-19 | — | — | EP | disclosed |
| EP-0730405-A1 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORPORATION (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014381-A1 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORPORATION (US) | 1995-06-01 | — | — | WO | disclosed |