Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.67 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.63 |
| ▸ | CNR1 | P21554 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860844 | 1.00 | LPAR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL21302818 | 0.96 | CNR1 (0.70) | LPAR1LPAR2ENPP2CNR1ALDH1A1 | |
| SCHEMBL9472268 | 0.93 | EPHX2 (0.66) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL9472257 | 0.93 | EPHX2 (0.66) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL28522605 | 0.92 | LPAR1 (0.58) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL23599314 | 0.92 | EPHX2 (0.68) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL11048269 | 0.92 | EPHX2 (0.58) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL14239787 | 0.91 | DNM1 (0.59) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL8920345 | 0.91 | DGKA (0.67) | LPAR1LPAR2ENPP2CNR1 | |
| SCHEMBL20856388 | 0.91 | DGKA (0.67) | LPAR1LPAR2ENPP2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059442-A | Primary amide esters as low calorie fat mimetics | NABISCO BRANDS, INC. (US) | 1991-10-22 | — | — | US | disclosed |