Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196344 | 0.82 | TDP1 (0.59) | NPC1RAB9AL3MBTL1KMT2ALMNA | |
| SCHEMBL17769820 | 0.81 | KMT2A (0.69) | MAOBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7625097 | 0.78 | TDP1 (0.46) | L3MBTL1KMT2AMEN1LMNACA12 | |
| SCHEMBL6646091 | 0.77 | MAOB (0.59) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL20597872 | 0.76 | MAOB (0.50) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7901756 | 0.74 | RAB9A (0.55) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7062567 | 0.73 | MAOB (0.69) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL18248023 | 0.73 | MAOB (0.50) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28481255 | 0.72 | RAB9A (0.52) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL17257319 | 0.72 | NPC1 (0.68) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |