Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | CSF1R | P07333 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900055 | 0.80 | EGFR (0.69) | MAP4K4CLK4TSHRCSF1REGFR | |
| Hydrochloric Acid SCHEMBL6039704 | 0.78 | EGFR (0.67) | MAP4K4CLK4LMNAMAPK1TSHR | |
| SCHEMBL4353946 | 0.77 | CSF1R (0.80) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL4353191 | 0.77 | EGFR (0.64) | MAP4K4CYP1A2CYP3A4CLK4LMNA | |
| SCHEMBL28054982 | 0.75 | PIK3CA (0.70) | MAP4K4CYP1A2CYP3A4LMNAMAPK1 | |
| SCHEMBL30395607 | 0.75 | CSF1R (0.55) | MAP4K4CYP1A2CYP3A4CLK4LMNA | |
| SCHEMBL29058819 | 0.75 | CSF1R (0.55) | MAP4K4CYP1A2CYP3A4CLK4LMNA | |
| SCHEMBL14189293 | 0.73 | MAP4K4 (0.65) | MAP4K4CYP1A2CYP3A4CLK4LMNA | |
| SCHEMBL15587451 | 0.73 | MAP4K4 (1.00) | MAP4K4 | |
| Hydrochloric Acid SCHEMBL8808017 | 0.72 | EGFR (0.61) | CYP1A2CYP3A4CLK4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |