Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.65 |
| ▸ | RXRG | P48443 | 8/20 | 0.65 |
| ▸ | RXRB | P28702 | 7/20 | 0.65 |
| ▸ | HNF4A | P41235 | 6/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917253 | 1.00 | RXRA (0.65) | RXRARXRGRXRBHNF4ACYP26A1 | |
| SCHEMBL6913487 | 1.00 | RXRA (0.65) | RXRARXRGRXRBHNF4ACYP26A1 | |
| SCHEMBL6913687 | 0.92 | RXRA (0.60) | RXRARXRGRXRBHNF4ACYP26A1 | |
| SCHEMBL6913425 | 0.90 | RXRA (0.58) | RXRARXRGRXRBHNF4A | |
| SCHEMBL6909567 | 0.89 | RXRA (0.69) | RXRARXRGRXRBHNF4A | |
| SCHEMBL6910100 | 0.89 | RXRA (0.69) | RXRARXRGRXRBHNF4A | |
| SCHEMBL6915899 | 0.86 | RXRA (0.76) | RXRARXRGRXRBHNF4A | |
| SCHEMBL6910041 | 0.85 | RXRA (0.69) | RXRARXRGRXRBHNF4A | |
| SCHEMBL6915796 | 0.83 | RXRA (0.65) | RXRARXRGRXRBHNF4A | |
| SCHEMBL6915944 | 0.83 | RXRA (0.75) | RXRARXRGRXRBHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012853-A1 | DIMER-SELECTIVE RXR MODULATORS AND METHODS FOR THEIR USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-04-10 | — | — | WO | claimed |