Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115275 | 0.90 | FAAH (0.47) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL114406 | 0.81 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL29174059 | 0.80 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28988028 | 0.80 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL23040949 | 0.79 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL29174024 | 0.79 | FAAH (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL29373613 | 0.77 | FAAH (0.48) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL30203250 | 0.77 | FAAH (0.48) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL7159921 | 0.74 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL6812418 | 0.74 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730405-A4 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORP (US) | 1997-02-19 | — | — | EP | disclosed |
| EP-0730405-A1 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORPORATION (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014381-A1 | AMPHIPHILIC DERIVATIVES OF GUANIDINE | MEGABIOS CORPORATION (US) | 1995-06-01 | — | — | WO | disclosed |