Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.98 |
| ▸ | THRB | P10828 | 1/20 | 0.98 |
| ▸ | KIF11 | P52732 | 5/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898607 | 0.99 | HTT (1.00) | HTTTHRBKIF11CTSVCTSL | |
| SCHEMBL29369556 | 0.99 | HTT (1.00) | HTTTHRBKIF11CTSVCTSL | |
| SCHEMBL8248041 | 0.99 | HTT (1.00) | HTTTHRBKIF11CTSVCTSL | |
| SCHEMBL8898611 | 0.99 | HTT (1.00) | HTTTHRBKIF11CTSVCTSL | |
| Hydrochloric Acid SCHEMBL31741907 | 0.98 | HTT (0.98) | HTTTHRBKIF11CTSVCTSL | |
| Hydrochloric Acid SCHEMBL1271897 | 0.98 | HTT (0.98) | HTTTHRBKIF11CTSVCTSL | |
| Hydrochloric Acid SCHEMBL1271899 | 0.98 | HTT (0.98) | HTTTHRBKIF11CTSVCTSL | |
| Hydrochloric Acid SCHEMBL1061360 | 0.98 | HTT (0.98) | HTTTHRBKIF11CTSVCTSL | |
| SCHEMBL8898190 | 0.87 | THRB (0.76) | HTTTHRBKIF11CTSVCTSL | |
| SCHEMBL8900565 | 0.86 | THRB (0.77) | HTTTHRBKIF11CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |