Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897353 | 0.89 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2TSHRMAPK1OPRM1 | |
| SCHEMBL8898762 | 0.85 | MAPT (0.46) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT | |
| SCHEMBL8897848 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL8898210 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL8896884 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL10889012 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRMAPK1OPRM1 | |
| SCHEMBL8899759 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL10888633 | 0.78 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2TSHRMAPK1OPRM1 | |
| SCHEMBL8899115 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TSHRMAPK1KDM4E | |
| Biphenyl SCHEMBL15988145 | 0.75 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629356-A | PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE | CIBA GEIGY CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| US-5554663-A | α-aminoacetophenones as photoinitiators | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0284561-B1 | ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5077402-A | For photocuring pigmented systems; printing inks, lacquers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0284561-A2 | Alpha-aminoacetophenones as photo initiators | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |