Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.53 |
| ▸ | PDE5A | O76074 | 2/20 | 0.53 |
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 1/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8907685 | 0.99 | NPY5R (0.59) | NPY5RKDM4EHTTTAAR1SLC2A1 | |
| SCHEMBL8901783 | 0.91 | NPY5R (0.69) | NPY5RSLC2A1ABCG2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8889859 | 0.90 | NPY5R (0.68) | NPY5RSLC2A1ABCG2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8912533 | 0.88 | NPY5R (0.68) | NPY5RSLC2A1PDE5A | |
| SCHEMBL8900016 | 0.86 | NPY5R (0.61) | NPY5RKDM4EHTTTAAR1SLC2A1 | |
| SCHEMBL8891464 | 0.85 | NPY5R (0.69) | NPY5RKDM4EHTTTAAR1SLC2A1 | |
| SCHEMBL8891851 | 0.85 | NPY5R (0.78) | NPY5RKDM4EHTTTAAR1ABCG2 | |
| SCHEMBL8901142 | 0.84 | NPY5R (0.51) | NPY5RSLC2A1 | |
| Hydrochloric Acid SCHEMBL8890929 | 0.84 | NPY5R (0.67) | NPY5RKDM4EHTTTAAR1SLC2A1 | |
| Hydrochloric Acid SCHEMBL8899399 | 0.84 | NPY5R (0.76) | NPY5RKDM4EHTTTAAR1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |