SCHEMBL8899345

SCHEMBL8899345

Nc1ccc(CCS(=O)(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.64
GFER P55789 1/20 0.54
CYP2D6 P10635 2/20 0.50
MAOB P27338 4/20 0.46
TSHR P16473 3/20 0.46
MAOA P21397 2/20 0.46
ALDH1A1 P00352 2/20 0.46
NT5E P21589 1/20 0.46
F2 P00734 2/20 0.44
TMPRSS4 Q9NRS4 2/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA6 P23280 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5262164 0.86 MAOB (0.53) RECQLGFERCYP2D6MAOBTSHR
SCHEMBL5336202 0.84 MAOB (0.52) RECQLGFERCYP2D6MAOBTSHR
Sulfuric Acid SCHEMBL8642565 0.84 GFER (0.70) RECQLGFERMAOBTSHRMAOA
SCHEMBL11281060 0.82 RECQL (0.69) RECQLGFERCYP2D6MAOBTSHR
SCHEMBL9653975 0.80 RECQL (0.41) RECQLGFERCYP2D6TSHRALDH1A1
SCHEMBL8145771 0.80 ESR1 (0.56) ALDH1A1TP53CYP3A4TDP1CA1
SCHEMBL2044233 0.80 RECQL (0.67) RECQLGFERMAOBTSHRMAOA
SCHEMBL11166463 0.80 RECQL (0.96) RECQLGFERMAOBTSHRMAOA
SCHEMBL3132188 0.78 RECQL (0.39) RECQLCYP2D6TSHRF2TMPRSS4
SCHEMBL7786905 0.78 PTGS1 (0.42) RECQLGFERCYP2D6TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997021666-A1 ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS GLAXO GROUP LIMITED (GB) 1997-06-19 WO disclosed