Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.70 |
| ▸ | MERTK | Q12866 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6039334 | 0.99 | NPY5R (0.69) | NPY5RMERTKMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL6039207 | 0.99 | NPY5R (0.69) | NPY5RMERTKMEN1KMT2ANPC1 | |
| SCHEMBL8900176 | 0.87 | NPY5R (0.53) | NPY5RMERTKSLC2A1ABCG2 | |
| Hydrochloric Acid SCHEMBL8890869 | 0.86 | NPY5R (0.52) | NPY5RSLC2A1KCNH3 | |
| Hydrochloric Acid SCHEMBL8890876 | 0.85 | ABCG2 (0.54) | NPY5RMERTKSLC2A1ABCG2 | |
| SCHEMBL8890917 | 0.83 | NPY5R (0.65) | NPY5RMERTKMEN1KMT2ANPC1 | |
| SCHEMBL8909187 | 0.83 | NPY5R (1.00) | NPY5RMERTKMEN1KMT2ANPC1 | |
| SCHEMBL8900365 | 0.83 | SLC2A1 (0.49) | NPY5RMERTKMEN1KMT2ANPC1 | |
| SCHEMBL8900353 | 0.83 | NPY5R (0.49) | NPY5RMERTKMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8889736 | 0.82 | NPY5R (0.63) | NPY5RMERTKMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |